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Document Type |
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Thesis |
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Document Title |
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“SYNTHESIS, MOLECULAR STRUCTURES AND CATALYTIC ACTIVITIES OF PALLADIUM (II) COMPLEXES CONTAINING 2-PHENYLPYRIDINE DERIVATIVES IN FORMATION OF C-C BOND” "تحضير و توصيف الأشكال البلورية و النشاطية الحفزية لمعقدات البلاديوم الثنائي المحتوية على مشتقات الفينايل بيريدين في تكوين روابط كربون-كربون" |
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Subject |
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Faculty of Science |
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Document Language |
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Arabic |
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Abstract |
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Phosphorus containing compounds have been widely used in cross-coupling reactions for the synthesis of heterocyclic and biaryl compounds. Phosphorus ligands also facilitate the formation of bulky and electron rich complexes. Phosphorus donor atoms have the ability to improve the catalytic activity when used to form transition metal complexes. However, over time, its extreme sensitivity to air and moisture has been of concern to chemist. Nitrogen donor ligands are seeing to be promising and could serve as a good alternative to the Phosphorus donor atoms.
Pyridine-based heterocyclic compounds synthesis continues to attract much attention due to their verse applicability on various fields including pharmaceutical and organic synthesis. In the Pharmaceutical industries, transition metals such as Palladium and copper complexes have been used successfully for the preparation of very active hypertensive drugs and researches are continually being carried out to explore more areas where these materials (Palladium catalysts) can be applied.
The preparation of a series of seven 2- phenylpyridine derivatives ligands; {2–(Mesityl) pyridine (L1), 2-(2, 6-dimethylphenyl) pyridine (L2), 2-(o-tolyl) pyridine (L3), 2-(m-tolyl) pyridine (L4), 2-(p-tolyl) pyridine (L5), 2-(o-Methoxyphenyl) pyridine (L6), 2-(p-Methoxyphenyl) pyridine (L7)} and their palladium complexes (PdCl2(L)2 where L= (L1-L7) were achieved. The new ligands and their complexes were characterized using a combination of X-ray diffraction spectroscopy, GC-MS and NMR. The crystal structures show that the Palladium complexes adopted a square planar geometry, the monodentate ligand coordinated through the N donor of pyridine ring to the Pd atom. The catalytic activities of the synthesized complexes were investigated. The square planar palladium complex trans ((2-mesitylpy)2 PdCl2) shows a high efficiency to proceed the Suzuki-Miyaura cross coupling in aqueous solvent under aerobic condition. |
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Supervisor |
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Dr. Ibrahim Mukhaled |
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Thesis Type |
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Master Thesis |
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Publishing Year |
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1441 AH
2019 AD |
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Added Date |
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Wednesday, September 25, 2019 |
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Researchers
| عبدالمعز ادا مسون | Mason, Abdel Moez Ada | Researcher | Master | |
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