Document Details

Document Type : Thesis 
Document Title :
EFFECT OF GRAPESEED OIL ON MALE RATS EXPOSED TO LEAD
تأثير زيت بذرة العنب على ذكور الجرذان المعرضة للرصاص
 
Subject : Faculty of Sciences 
Document Language : Arabic 
Abstract : Objective: The present study was aimed to examine the effect of grape seed oil on toxicity induced by lead (Pb) in Wistar male rats. Materials and Methods: Four groups of rats were used in this experiment, rats of the first group were served as control. The second group was exposed to Pb (100 mg/kg). Rats of the third group were treated with grape seed oil (600 mg/kg) plus Pb. The fourth group was supplemented with grape seed oil. After six weeks, physiological and histopathological alterations were estimated. Results: Statistically, no significant changes were observed in body weights in the experimental rats. Significant alteration of serum creatinine was detected in Pb-treated rats. While a significant alteration of serum blood urea nitrogen (BUN) was observed in grape seed oil plus Pb treated rats. Histopathologically, the sections of liver, kidney and testis from Pb-treated rats revealed some changes. In conclusion, the present study demonstrates that grape seed oil slightly attenuated the physiological and histological alterations induced by Pb. Furthermore, the result of the present study suggests that the antioxidant properties of grape seed oil could be attributed to the protective effect against toxicity induced by Pb. 
Supervisor : Prof. Dr. Samar Omar Abdullah Rabah 
Thesis Type : Master Thesis 
Publishing Year : 1440 AH
2018 AD 
Co-Supervisor : Dr. Ghada Ahmed El Hag Mohammed 
Added Date : Tuesday, October 23, 2018 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
ندى عبد الرحمن علويAlawi, Nada Abdul RahmanResearcherMaster 

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