Document Details

Document Type : Thesis 
Document Title :
Synthesis of Some new fluorine substituted thiobarbituric acids and Their Related Systems as Potential Inhibitors against some
تشييد بعض مشتقات حمض الثيوباربتيورك الفلورية الجديدة والأنظمة المقابلة لها كعوامل مثبطة لنشاط بعض الفيروسات .
 
Subject : Chemistry department 
Document Language : Arabic 
Abstract : Some more new fluorine substituted thiobarbituric acids (2-14) and (16-26) have been synthesized from ring closure of thioureas (1) with malonic acid or 1,3-diketoamine (15) with carbon disulfide. Also, fluorinated fused/isolated heterobicyclic nitrogen systems were obtained by using the chemical activity of carbon-5 of fluorinated thiobarbituric acids. The structures of the targets have been established by the help of elemental analyses and spectral data. Use of the obtained targets as potential inhibitors have been deduced against HIV-1 and CDK2, Kinase in the human cells. 
Supervisor : Prof Dr. Reda M. Abdel-Rahman 
Thesis Type : Master Thesis 
Publishing Year : 1434 AH
2013 AD 
Co-Supervisor : Prof Dr. Abdullah M. Asiri 
Added Date : Wednesday, December 4, 2013 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
عبدالرحمن سالم الحربيAl-Harbi, Abdulrahman SalimResearcherMaster 

Files

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 36394.pdf pdf 

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