Document Details
|
Document Type |
: |
Article In Journal |
|
Document Title |
: |
The use of chloral hydrate in pediatric electroencephalography The use of chloral hydrate in pediatric electroencephalography |
|
Document Language |
: |
English |
|
Abstract |
: |
Objective: Sleep is a known activator of epileptiform
discharges on electroencephalography. Chloral hydrate is
used frequently for electroencephalography sedation. Our
objectives were to study the value and limitations of
chloral hydrate.
Methods: One hundred and fifty nine consecutive
pediatric electroencephalograms were included
prospectively. One electroencephalography technologist
collected chloral hydrate related data.
Electroencephalogram requisitions and recordings were
reviewed separately by one certified
electroencephalographer.
Results: The children’s ages ranged between 8 days to
19 years (mean=5.7 years). Natural sleep was recorded in
11% and only 2% were sleep deprived. Sedation was given
to 45% mostly using chloral hydrate (96%). Children with
chronic neurological abnormalities were more likely to
receive chloral hydrate (odds ratio=9.8, 95% confidence
The use of chloral hydrate in pediatric
electroencephalography
Mohammed M.S. Jan, MBChB, FRCP (C), Marilou F. Aquino, EEG Tech.
From the Department of Neurosciences (Jan), King Faisal Specialist Hospital and Research Center and The Neurophysiology Unit (Aquino), King
Abdulaziz University Hospital, Jeddah, Kingdom of Saudi Arabia.
Received 29th August 2000. Accepted for publication in final form 12th December 2000.
Address correspondence and reprint request to: Dr Mohammed M.S. Jan, Department of Neurosciences, King Faisal Specialist Hospital & Research
Center, MCB J-76, PO Box 40047, Jeddah 21499, Kingdom of Saudi Arabia. Tel. 00 966 2 667 7777 Ext 5819. Fax. 00966 2 667 7777 Ext 5813.
interval=4.5-21). Chloral hydrate was effective in inducing
sleep in 97%, however, 34% of the children woke up
spontaneously before the test was completed, particularly
those with chronic neurological abnormalities (p=0.0003).
A second dose was necessary in 13%. Recording an initial
period of wakefulness followed by sleep onset was more
likely achieved in natural sleep electroencephalograms
when compared to the sedated group (82% vs 10%,
p<0.0001). These electroencephalograms were more likely
to contain epileptiform discharges (p<0.001).
Conclusion: Although chloral hydrate was effective in
sleep induction, the sleep onset was frequently missed and
the hypnotic effects were not sustained, particularly in
children with chronic neurological abnormalities. |
|
ISSN |
: |
1658-3183 |
|
Journal Name |
: |
Neurosciences |
|
Volume |
: |
6 |
|
Issue Number |
: |
2 |
|
Publishing Year |
: |
1422 AH
2001 AD |
|
Article Type |
: |
Article |
|
Added Date |
: |
Sunday, April 20, 2008 |
|
Researchers
| محمد جان | Jan, Mohammed | Investigator | Doctorate | |
|
Files
|
Chloral.pdf
| pdf | مشاهدة المقالة العلمية كاملة |
|
Back To Researches Page
|